"The artwork, room view was great, reusable water bottles"
Valarie from United States
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"Beautiful, well-appointed luxurious corner king room with amazing view of the city."
Gina M from United States
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"Enjoyed the blue penguins in the hall and the rubber duck in the bathroom for some whimsy!"
NLF2013 from United States
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"A lovely hotel in the heart of Downtown Lexington. It has a cute art gallery within the reception."
Lianne H from United States
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"Amazing decor and perfect location"
John from United States
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4-star art-infused boutique hotel in Lexington
Art and Museums
21c Museum Hotel Lexington boasts over 7,000 square feet of exhibition space featuring contemporary art. The property includes both solo and group exhibitions that reflect contemporary culture, with specially commissioned works by notable artists throughout the hotel. Guests regularly find installations like 'Totally in Love' by Pieke Bergman and 'Spectralline' by SOFTlab in prominent locations.
Dining Options
Lockbox, the on-site restaurant, offers a menu that highlights local ingredients while showcasing Kentucky's rich culinary heritage. Guests can enjoy breakfast, lunch, and dinner sourced from regional suppliers. The bar at Lockbox serves a variety of local beers, creative cocktails, and Kentucky Bourbons.
Accommodation Choices
The hotel provides a variety of room types, including the City Queen, Deluxe King, and the expansive 21c Suite with views of downtown Lexington. Each room is equipped with original artwork, custom-designed contemporary furnishings, and luxurious bedding from Malin + Goetz. Unique rooms, such as Nightwatch, offer immersive art environments that enhance the overall stay.
Event Facilities
21c Museum Hotel offers an array of event spaces, accommodating gatherings of up to 250 people. The main gallery is suitable for seated events of up to 112 guests, while five private galleries are available for smaller meetings. The hotel also provides state-of-the-art audiovisual capabilities for all corporate needs.
Location and Connectivity
Situated in downtown Lexington, the hotel lies at the intersection of southern charm and urban life. It serves as a strategic base for exploring local breweries, horse farms, and cultural landmarks within the city. Nearby attractions include the vibrant street art scene and various bourbon distilleries.
Highlights
Art: 7,000 square feet of exhibition space
Dining: Lockbox restaurant showcasing local cuisine
Rooms: City Queen, Deluxe King & 21c Suite options
Events: Main gallery with flexible seating capacities
“The art concept permeates the hotel, from public spaces to well-appointed rooms, creating a sophisticated atmosphere. Service is consistently attentive, and the downtown location proves very convenient for exploring local attractions. It's a genuinely stylish base in Lexington.”
James DavidEditor-in-Chief at Uskentucky
Select your room type
21C Museum Hotel Lexington offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
City Queen Room
2 persons
22 sq. feet
1 King-size bed
Air conditioning
Heating
room details
Deluxe Queen Room
2 persons
33 sq. feet
2 King Size Beds
Air conditioning
Heating
room details
Deluxe King Room
2 persons
31 sq. feet
1 King-size bed
Air conditioning
Heating
room details
Show all rooms
Price and Room Availability Calendar
Check availability and prices for your dates now!
June 2026 - June 2027
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Check-in/ Check-out
Facilities
21C Museum Hotel Lexington offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.3/10Review score
General
No smoking on site
Free Wi-Fi in public areas
Safe deposit box
24-hour reception
VIP check-in/ -out
Pets allowed
Rooms/ Facilities for disabled
24-hour security
Luggage storage
Allergy-free rooms
Lift
ATM/Cash machine
Vending machines
Smoke detectors
Fire extinguishers
Key card access
Key access
Sports & Fitness
Fitness centre
Yoga class
Services
Paid shuttle service
Room service
Housekeeping
Laundry
Dry cleaning
Tours/Ticket assistance
Welcome drink
Dining
In-room breakfast
Restaurant
Snack bar
Bar/ Lounge area
Special diet menus
Business
Business centre
Meeting/ Banquet facilities
Fax/Photocopying
Children
Children's menu
Room features
Air conditioning
Heating
Soundproofed rooms
Sitting area
Dressing area
Tea and coffee facilities
Dining table
Ironing facilities
Bathroom
Free toiletries
Media
Flat-screen TV
AM/FM alarm clock
Show more
Dining Onsite
At 21C Museum Hotel Lexington, dining transforms into a delightful exploration of local flavors and sustainable practices. Lockbox offers a contemporary American menu, while nearby options like La Cabana and Miguel's Pizza bring vibrant culinary experiences, perfect for indulging after a day of adventures.
Lockbox
American, Local
Ambiance
A modern space that fuses artistry with comfort, Lockbox welcomes guests to unwind in a stylish yet relaxed setting.
Key Offerings
The culinary team can create a tailored catering menu to suit special occasions, with options accommodating vegetarian, vegan, gluten-free, and dairy-free diets. Highlights include innovative takes on classic dishes, beautifully presented.
Reservation
Recommended
Open for breakfast and dinner
La Cabana Mexican Restaurant
Mexican
Ambiance
A lively and colorful eatery, La Cabana embodies the spirit of Mexico, where guests are enveloped in a festive atmosphere ideal for groups and families.
Key Offerings
Famous for its hearty burritos and refreshing margaritas, this family-friendly café focuses on sustainability, sourcing ingredients locally for a more authentic taste.
Reservation
Not needed
Hours vary
Miguel's Pizza
Pizza
Ambiance
Renowned for its cozy, casual vibe, Miguel's Pizza is the perfect spot to gather with friends after a long day, offering a laid-back environment.
Key Offerings
A local favorite recognized for its delicious pizza slices, Miguel's has something for everyone looking to indulge in comfort food.
Reservation
Not needed
Hours vary
21C Museum Hotel Lexington Location
167 West Main Street, Lexington, 40507,
Explore Lexington
Explore Lexington
Top Attractions
Activities
Dining
Entertainment
Rupp Arena
6 minutes' walk
Home to concerts and sports events, Rupp Arena is a vibrant venue with a storied history and seating for over 23,000.
University of Kentucky Art Museum
13 minutes' walk
Showcasing local and international art, this museum features changing exhibitions and a lovely setting for art lovers.
Transylvania University
10 minutes' walk
Established in 1780, notable for its historic campus and beautiful architecture, providing rich cultural insights.
Lexington Cemetery
4 minutes' drive
A peaceful space featuring stunning monuments and nature trails, perfect for leisurely strolls or reflection.
Horse Country Farm Tours
12 minutes' walk
Guided tours showcasing thoroughbred farms, providing a unique insight into Kentucky's equestrian culture.
The Arboretum
10 minutes' drive
A beautiful park with walking trails and gardens, ideal for relaxation or family picnics in a serene environment.
Bourbon on Rye
1 minute' walk
This casual spot offers Southern favorites and an extensive bourbon selection, perfect for a laid-back meal.
Corto Lima
3 minutes' walk
An upscale eatery serving fresh, farm-to-table Mexican cuisine, known for vibrant flavors and a cozy atmosphere.
School Sushi
2 minutes' walk
Offering creative sushi rolls in a trendy setting, great for a casual meal or takeout option for busy travelers.
Kentucky Theatre
5 minutes' walk
A historic cinema showing independent films and classic movies, offering an intimate setting for film enthusiasts.
WoodSongs Old-Time Radio Hour
10 minutes' walk
A weekly live music show featuring local and international artists, fostering a sense of community through music.
Getting around
City Centre
Lexington 5 min · 1400 ft
Airports
Blue Grass (LEX) 21 min · 8.5 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room. There are no cots provided in a room.
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
88
Reviews and Ratings
Feedback about 21C Museum Hotel Lexington from previous guests about their experience.
Review score
Based on 439 verified reviews
8.2 /10
Great
75 %
Recommend
Cleanliness
8.5/10
Comfort
8.5/10
Facilities
8.3/10
Free WiFi
8.0/10
Location
8.9/10
Staff
8.6/10
Value for money
7.7/10
Pros
Historic building
Comfortable rooms
Art collection
Cons
Overpriced drinks
Room temperature issues
WiFi connectivity
Guest reviews
based on 300 reviews
8.0/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.